GRK6 polyclonal antibody
产品名称： GRK6 polyclonal antibody
英文名称： GRK6 polyclonal antibody
产品编号： PAB2681
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GRK6.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human GRK6.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein-coupled receptor kinase-mediated phosphorylation and agonist-mediated desensitization.
Teli T, Markovic D, Levine MA, Hillhouse EW, Grammatopoulos DK.Mol Endocrinol. 2005 Feb;19(2):474-90. Epub 2004 Oct 21.
- 2.
- Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells.
Hagen SA, Kondyra AL, Grocott HP, El-Moalem H, Bainbridge D, Mathew JP, Newman MF, Reves JG, Schwinn DA, Kwatra MM.Anesthesiology. 2003 Feb;98(2):343-8.
- 3.
- Aberrantly expressed recoverin is functionally associated with G-protein-coupled receptor kinases in cancer cell lines.
Miyagawa Y, Ohguro H, Odagiri H, Maruyama I, Maeda T, Maeda A, Sasaki M, Nakazawa M.Biochem Biophys Res Commun. 2003 Jan 17;300(3):669-73.
- Entrez GeneID:
- 2870
- Protein Accession#:
- NP_001004106;P43250
- Gene Name:
- GRK6
- Gene Alias:
- FLJ32135,GPRK6
- Gene Description:
- G protein-coupled receptor kinase 6
- Omim ID:
- 600869
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- -
- Gene Pathway